Chemical Modifications Influence the Number of siRNA Molecules Adsorbed on Gold Nanoparticles and the Efficiency of Downregulation of a Target Protein.

Epanchintseva, Anna V; Poletaeva, Julia E; Dome, Anton S; Dovydenko, Ilya S; Pyshnaya, Inna A; Ryabchikova, Elena I

Epanchintseva, Anna V; Poletaeva, Julia E; Dome, Anton S; Dovydenko, Ilya S; Pyshnaya, Inna A; Ryabchikova, Elena I.

Afiliação

Epanchintseva AV; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.
Poletaeva JE; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.
Dome AS; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.
Dovydenko IS; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.
Pyshnaya IA; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.
Ryabchikova EI; Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk 630090, Russia.

Nanomaterials (Basel) ; 12(24)2022 Dec 14.

Article em En | MEDLINE | ID: mdl-36558301

Palavras-chave

efficiency of silencing; modified siRNA; multilevel nanoconstruct; phosphoryl guanidine modification; siRNA adsorption on AuNPs

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Nanomaterials (Basel) Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Federação Russa

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