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Case report: Exploring under the tip of the iceberg: A case series of "self-limiting" multisystem inflammatory syndrome in children.
Meneghel, Alessandra; Martini, Giorgia; Balzarin, Marta; Zabadneh, Nadia; Fastiggi, Michele; Tirelli, Francesca; Zulian, Francesco.
Afiliação
  • Meneghel A; Pediatric Rheumatology Unit, Department for Women's and Children's Health, University Hospital of Padova, Padova, Italy.
  • Martini G; Pediatric Rheumatology Unit, Department for Women's and Children's Health, University Hospital of Padova, Padova, Italy.
  • Balzarin M; Pediatric Unit, "San Bortolo" Hospital, Vicenza, Italy.
  • Zabadneh N; Pediatric Unit, "Ospedali Riuniti Padova Sud" Hospital, Schiavonia, Italy.
  • Fastiggi M; Pediatric Rheumatology Unit, Department for Women's and Children's Health, University Hospital of Padova, Padova, Italy.
  • Tirelli F; Pediatric Rheumatology Unit, Department for Women's and Children's Health, University Hospital of Padova, Padova, Italy.
  • Zulian F; Pediatric Rheumatology Unit, Department for Women's and Children's Health, University Hospital of Padova, Padova, Italy.
Front Pediatr ; 10: 1012582, 2022.
Article em En | MEDLINE | ID: mdl-36582511
Multisystem inflammatory syndrome in children (MIS-C) is a serious condition triggered by SARS-COV-2 infection, characterized by persistent fever, multiorgan dysfunction, and increased inflammatory markers. It requires hospitalization and prompt treatment, with nearly 60% of the cases needing intensive care and 2% fatality rate. A wide spectrum of clinical characteristics and therapeutic approaches has been reported in MIS-C. We describe a series of four patients with MIS-C, defined according to the current case definitions, with a self-limiting course and no need for immunomodulatory treatment ("self-limiting MIS-C"). Few data about self-limiting MIS-C are available to date and no information on medium- and long-term outcome of this subset of patients has been reported. Although limited in size, our experience provides new insights into the MIS-C syndrome, highlighting an underestimated aspect of the disease that may have significant therapeutic implications.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pediatr Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Front Pediatr Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Itália