Effectiveness and feasibility of cardiovascular disease personalized prevention on high polygenic risk score subjects: a randomized controlled pilot study.

Viigimaa, Margus; Jürisson, Mikk; Pisarev, Heti; Kalda, Ruth; Alavere, Helene; Irs, Alar; Saar, Aet; Fischer, Krista; Läll, Kristi; Kruuv-Käo, Krista; Mars, Nina; Widen, Elisabeth; Ripatti, Samuli; Metspalu, Andres

Viigimaa, Margus; Jürisson, Mikk; Pisarev, Heti; Kalda, Ruth; Alavere, Helene; Irs, Alar; Saar, Aet; Fischer, Krista; Läll, Kristi; Kruuv-Käo, Krista; Mars, Nina; Widen, Elisabeth; Ripatti, Samuli; Metspalu, Andres.

Afiliação

Viigimaa M; Department of Health Technologies, Tallinn University of Technology, Ehitajate tee 5, 19086 Tallinn, Estonia.
Jürisson M; Centre of Cardiology, North Estonia Medical Centre, Sütiste St. 19, 13419 Tallinn, Estonia.
Pisarev H; Institute of Family Medicine and Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia.
Kalda R; Institute of Family Medicine and Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia.
Alavere H; Institute of Family Medicine and Public Health, University of Tartu, Ravila 19, 50411 Tartu, Estonia.
Irs A; Institute of Genomics, University of Tartu, Riia 23b, 51010 Tartu, Estonia.
Saar A; Heart Clinic, Tartu University Hospital, L. Puusepa 8, 50406 Tartu, Estonia.
Fischer K; Centre of Cardiology, North Estonia Medical Centre, Sütiste St. 19, 13419 Tallinn, Estonia.
Läll K; Heart Clinic, University of Tartu, L. Puusepa 8, 50406 Tartu, Estonia.
Kruuv-Käo K; Institute of Genomics, University of Tartu, Riia 23b, 51010 Tartu, Estonia.
Mars N; Institute of Mathematics and Statistics, University of Tartu, Narva mnt 18, 51009 Tartu, Estonia.
Widen E; Institute of Genomics, University of Tartu, Riia 23b, 51010 Tartu, Estonia.
Ripatti S; Institute of Genomics, University of Tartu, Riia 23b, 51010 Tartu, Estonia.
Metspalu A; Institute for Molecular Medicine Finland, University of Helsinki, Tukholmankatu 8, 00014 Helsinki, Finland.

Eur Heart J Open ; 2(6): oeac079, 2022 Nov.

Article em En | MEDLINE | ID: mdl-36600884

Palavras-chave

Polygenic risk score; coronary artery disease; personalized prevention

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Clinical_trials / Etiology_studies / Risk_factors_studies Idioma: En Revista: Eur Heart J Open Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Estônia

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