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[Factors Influencing Suicide Deaths in Patients With Schizophrenia Based on Cohort Data: An Empirical Study of a Sample of 170006 Patients in Sichuan Province].
Li, Shuo; Yang, Xian-Mei; Wang, Dan; Fan, Ruo-Xin; Tian, Shao-Li; Wang, Rong-Ke; Xiang, Hu; Zhang, Qiang; Liu, Yuan-Yuan; Liu, Xiang.
Afiliação
  • Li S; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
  • Yang XM; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Wang D; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Fan RX; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Tian SL; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Wang RK; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Xiang H; The Third Hospital of Mianyang and Sichuan Mental Health Center, Mianyang 621000, China.
  • Zhang Q; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
  • Liu YY; West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
  • Liu X; Department of Health Behavior and Social Medicine, West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu 610041, China.
Sichuan Da Xue Xue Bao Yi Xue Ban ; 54(1): 142-147, 2023 Jan.
Article em Zh | MEDLINE | ID: mdl-36647657
ABSTRACT

Objective:

To prospectively explore the risk factors of suicide in patients with schizophrenia.

Methods:

Data on schizophrenia patients in Sichuan Province between 2006 and 2018 were obtained from the National Severe Mental Disorders Information System, and the Cox proportional hazards regression model was used to explore for risk factors for suicide in schizophrenia patients.

Result:

A total of 170006 patients with schizophrenia were included in the study. At the end of the follow-up period, 160570 patients were alive and 9436 died from various causes, 929 of which being suicide deaths, resulting in a suicide rate of 223.61/100, 000 person-years. The Cox proportional hazards regression model suggested that risk factors for suicide in patients with schizophrenia included poverty ( HR=1.20, 95% CI 1.02-1.41), higher education level (primary school [ HR=1.32, 95% CI 1.09-1.60], middle school [ HR=1.40, 95% CI 1.14-1.73], high school and above [ HR=1.93, 95% CI 1.49-2.52]) in comparison with illiteracy and semi-literacy, suicide attempts ( HR=2.70, 95% CI 1.70-4.29), strict medication compliance ( HR=1.91, 95% CI 1.66-2.20), history of antipsychotic drug therapy ( HR=1.42, 95% CI 1.06-1.90), younger age group of patients of 46-60 ( HR=1.95, 95% CI 1.60-2.39), 31-45 ( HR=3.61, 95% CI 2.92-4.47), and 15-30 ( HR=12.37, 95% CI 9.69-15.78) compared with the 61-90 age group, and doing agriculture jobs ( HR=1.36, 95% CI 1.13-1.65).

Conclusion:

Young and middle-aged schizophrenia patients with higher education levels, especially those with a history of suicide attempts, are at high risk for suicide. Focused interventions should be directed at high-risk groups to reduce suicide deaths in patients with schizophrenia.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Middle aged País/Região como assunto: Asia Idioma: Zh Revista: Sichuan Da Xue Xue Bao Yi Xue Ban Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Esquizofrenia Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans / Middle aged País/Região como assunto: Asia Idioma: Zh Revista: Sichuan Da Xue Xue Bao Yi Xue Ban Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China