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Using heparan sulfate octadecasaccharide (18-mer) as a multi-target agent to protect against sepsis.
Liao, Yi-En; Xu, Yongmei; Arnold, Katelyn; Zhang, Fuming; Li, Jine; Sellers, Rani; Yin, Chaoyin; Pagadala, Vijayakanth; Inman, Anna Marie; Linhardt, Robert J; Xu, Ding; Pawlinski, Rafal; Liu, Jian.
Afiliação
  • Liao YE; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
  • Xu Y; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
  • Arnold K; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
  • Zhang F; Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180.
  • Li J; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
  • Sellers R; Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina, Chapel Hill, NC 27599.
  • Yin C; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
  • Pagadala V; Glycan Therapeutics Corporation, Raleigh, NC 27606.
  • Inman AM; Glycan Therapeutics Corporation, Raleigh, NC 27606.
  • Linhardt RJ; Department of Chemistry and Chemical Biology, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180.
  • Xu D; Department of Oral Biology, School of Dental Medicine, The State University of New York at Buffalo, Buffalo, NY 14215.
  • Pawlinski R; Division of Hematology, Department of Medicine, Blood Research Center, University of North Carolina, Chapel Hill, NC 27599.
  • Liu J; Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina, Chapel Hill, NC 27599.
Proc Natl Acad Sci U S A ; 120(4): e2209528120, 2023 01 24.
Article em En | MEDLINE | ID: mdl-36649428
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sepse / Endotoxemia / Proteína HMGB1 Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sepse / Endotoxemia / Proteína HMGB1 Limite: Animals Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2023 Tipo de documento: Article