RNA sequence to structure analysis from comprehensive pairwise mutagenesis of multiple self-cleaving ribozymes.

Roberts, Jessica M; Beck, James D; Pollock, Tanner B; Bendixsen, Devin P; Hayden, Eric J

Roberts, Jessica M; Beck, James D; Pollock, Tanner B; Bendixsen, Devin P; Hayden, Eric J.

Afiliação

Roberts JM; Biomolecular Sciences Graduate Programs, Boise State University, Boise, United States.
Beck JD; Computing PhD Program, Boise State University, Boise, United States.
Pollock TB; Department of Biological Science, Boise State University, Boise, United States.
Bendixsen DP; Biomolecular Sciences Graduate Programs, Boise State University, Boise, United States.
Hayden EJ; Biomolecular Sciences Graduate Programs, Boise State University, Boise, United States.

Elife ; 122023 01 19.

Article em En | MEDLINE | ID: mdl-36655987

Assuntos

RNA Catalítico; RNA Catalítico/metabolismo; RNA; Sequência de Bases; Nucleotídeos; Mutagênese; Conformação de Ácido Nucleico

Palavras-chave

RNA; biochemistry; chemical biology; epistasis; fitness landscape; genotype to phenotype; molecular biophysics; none; ribozyme; sequence to function; structural biology

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Catalítico Tipo de estudo: Prognostic_studies Idioma: En Revista: Elife Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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