Geniposide promotes splenic Treg differentiation to alleviate colonic inflammation and intestinal barrier injury in ulcerative colitis mice.

Yu, Yun; Bian, Yong; Shi, Jian-Xin; Gu, Yu; Yuan, Dong-Ping; Yu, Bin; Shi, Le; Dou, Da-Hai

Yu, Yun; Bian, Yong; Shi, Jian-Xin; Gu, Yu; Yuan, Dong-Ping; Yu, Bin; Shi, Le; Dou, Da-Hai.

Afiliação

Yu Y; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Bian Y; Laboratory Animal Center, Nanjing University of Chinese Medicine, Nanjing, China.
Shi JX; Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing, China.
Gu Y; School of Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Yuan DP; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Yu B; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Shi L; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Dou DH; Department of Pharmacy, Jiangsu Province Hospital, Nanjing, China.

Bioengineered ; 13(6): 14616-14631, 2022 06.

Article em En | MEDLINE | ID: mdl-36694912

Assuntos

Colite Ulcerativa; Humanos; Camundongos; Animais; Colite Ulcerativa/tratamento farmacológico; Colite Ulcerativa/metabolismo; Fator de Necrose Tumoral alfa/metabolismo; Células CACO-2; Linfócitos T Reguladores/metabolismo; Baço; Lipopolissacarídeos/metabolismo; Inflamação/metabolismo; Fatores de Transcrição Forkhead/metabolismo; Diferenciação Celular; Camundongos Endogâmicos C57BL; Modelos Animais de Doenças

Palavras-chave

Geniposide; Treg; immunity; inflammation; spleen; ulcerative colitis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite Ulcerativa Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Bioengineered Ano de publicação: 2022 Tipo de documento: Article País de afiliação: China

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