Extracellular vesicle proteomics and phosphoproteomics identify pathways for increased risk in patients hospitalized with COVID-19 and type 2 diabetes mellitus.

Nunez Lopez, Yury O; Iliuk, Anton; Casu, Anna; Parikh, Amay; Smith, Joshua S; Corbin, Karen; Lupu, Daniel; Pratley, Richard E

Nunez Lopez, Yury O; Iliuk, Anton; Casu, Anna; Parikh, Amay; Smith, Joshua S; Corbin, Karen; Lupu, Daniel; Pratley, Richard E.

Afiliação

Nunez Lopez YO; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States.
Iliuk A; Department of Biochemistry, Purdue University, West Lafayette, IN 47907, United States; Tymora Analytical Operations, West Lafayette, IN 47906, United States. Electronic address: anton.iliuk@tymora-analytical.com.
Casu A; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States.
Parikh A; Division of Critical Care, AdventHealth Medical Group, AdventHealth Orlando, Orlando, FL 32804, United States.
Smith JS; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States.
Corbin K; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States.
Lupu D; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States.
Pratley RE; Translational Research Institute, AdventHealth Orlando, Orlando, FL 32804, United States. Electronic address: Richard.Pratley.MD@AdventHealth.com.

Diabetes Res Clin Pract ; 197: 110565, 2023 Mar.

Article em En | MEDLINE | ID: mdl-36736734

Assuntos

COVID-19; Diabetes Mellitus Tipo 2; Vesículas Extracelulares; Humanos; COVID-19/metabolismo; Diabetes Mellitus Tipo 2/patologia; SARS-CoV-2; Proteômica; Proteínas Quinases Ativadas por AMP/metabolismo; Vesículas Extracelulares/metabolismo; Quinases Associadas a rho/metabolismo

Palavras-chave

Acute respiratory disease; COVID-19; COVID-19 and diabetes interaction; Exosome; Extracellular vesicle; Hospitalized patient; Phosphoproteomics; Proteomics; Type 2 diabetes mellitus

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Vesículas Extracelulares / COVID-19 Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Diabetes Res Clin Pract Assunto da revista: ENDOCRINOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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