Corynebacterium kroppenstedtii breast abscesses in context, a retrospective cohort study.
J Med Microbiol
; 71(12)2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-36748506
ABSTRACT
Corynebacterium kroppenstedtii breast abscesses and granulomatous mastitis have gained increased recognition in the 20 years since their association was first described. No studies to date have described this organism in the context of all breast abscess pathogens. We retrospectively reviewed 160 community-acquired breast abscess samples from 135 patients in a 3 year period, describing the organisms isolated along with risk factors, site of infection and outcomes. We compared patient subgroups with acute and chronic abscesses, the latter defined as having a requirement for repeat aspiration more than 1 month apart. The prevalence of C. kroppenstedtii breast abscesses was 8â% in all patients (11/135), rising to 32â% in chronic abscesses (10/31), but only 1â% in acute abscesses (1/104; P<0.01). Only 10â% (1/10) of patients with C. kroppenstedtii chronic abscesses were smokers, whereas 75â% of patients (15/20) with non-C. kroppenstedtii chronic abscesses were smokers (P=0.01). C. kroppenstedtii should be considered in recurrent and prolonged infections, especially in non-smokers, and diagnostic methods altered accordingly. Identifying C. kroppenstedtii provides diagnostic clarity and alters management with recommendations for longer courses of treatment using non-beta-lactam antibiotics.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções por Corynebacterium
/
Abscesso
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
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Guideline
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
Idioma:
En
Revista:
J Med Microbiol
Ano de publicação:
2022
Tipo de documento:
Article
País de afiliação:
Reino Unido