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NIR luminogen for low-temperature photothermal therapy by triggering HSP90α down-regulation.
Yang, Xinzhe; Ding, Keke; Zhang, Guiquan; Han, Pengbo; Hu, Rong; Wang, Zhiming; Qin, Anjun; Tang, Ben Zhong.
Afiliação
  • Yang X; State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou, 510640, China. msqinaj@scut.edu.cn.
  • Ding K; Center for Aggregation-Induced Emission, AIE Institute, South China University of Technology, Guangzhou, 510640, China.
  • Zhang G; Department of Urology, The First Affiliated Hospital of Soochow University, NO. 188 Shizi Road, Suzhou, 215006, China.
  • Han P; State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou, 510640, China. msqinaj@scut.edu.cn.
  • Hu R; Center for Aggregation-Induced Emission, AIE Institute, South China University of Technology, Guangzhou, 510640, China.
  • Wang Z; State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou, 510640, China. msqinaj@scut.edu.cn.
  • Qin A; Center for Aggregation-Induced Emission, AIE Institute, South China University of Technology, Guangzhou, 510640, China.
  • Tang BZ; State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates, South China University of Technology, Guangzhou, 510640, China. msqinaj@scut.edu.cn.
Chem Commun (Camb) ; 59(19): 2743-2746, 2023 Mar 02.
Article em En | MEDLINE | ID: mdl-36751850
A near-infrared (NIR) luminogen TST was designed and used to efficiently trigger HSP90α protein knockdown through photo-thermal conversion based on a gene interference strategy, by which in vitro and in vivo tumor ablation were significantly acquired at low-temperature.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipertermia Induzida / Neoplasias Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hipertermia Induzida / Neoplasias Limite: Humans Idioma: En Revista: Chem Commun (Camb) Assunto da revista: QUIMICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China