Racial/Ethnic Disparities in Post-acute Sequelae of SARS-CoV-2 Infection in New York: an EHR-Based Cohort Study from the RECOVER Program.
J Gen Intern Med
; 38(5): 1127-1136, 2023 04.
Article
em En
| MEDLINE
| ID: mdl-36795327
ABSTRACT
BACKGROUND:
Compared to white individuals, Black and Hispanic individuals have higher rates of COVID-19 hospitalization and death. Less is known about racial/ethnic differences in post-acute sequelae of SARS-CoV-2 infection (PASC).OBJECTIVE:
Examine racial/ethnic differences in potential PASC symptoms and conditions among hospitalized and non-hospitalized COVID-19 patients.DESIGN:
Retrospective cohort study using data from electronic health records.PARTICIPANTS:
62,339 patients with COVID-19 and 247,881 patients without COVID-19 in New York City between March 2020 and October 2021. MAINMEASURES:
New symptoms and conditions 31-180 days after COVID-19 diagnosis. KEYRESULTS:
The final study population included 29,331 white patients (47.1%), 12,638 Black patients (20.3%), and 20,370 Hispanic patients (32.7%) diagnosed with COVID-19. After adjusting for confounders, significant racial/ethnic differences in incident symptoms and conditions existed among both hospitalized and non-hospitalized patients. For example, 31-180 days after a positive SARS-CoV-2 test, hospitalized Black patients had higher odds of being diagnosed with diabetes (adjusted odds ratio [OR] 1.96, 95% confidence interval [CI] 1.50-2.56, q<0.001) and headaches (OR 1.52, 95% CI 1.11-2.08, q=0.02), compared to hospitalized white patients. Hospitalized Hispanic patients had higher odds of headaches (OR 1.62, 95% CI 1.21-2.17, q=0.003) and dyspnea (OR 1.22, 95% CI 1.05-1.42, q=0.02), compared to hospitalized white patients. Among non-hospitalized patients, Black patients had higher odds of being diagnosed with pulmonary embolism (OR 1.68, 95% CI 1.20-2.36, q=0.009) and diabetes (OR 2.13, 95% CI 1.75-2.58, q<0.001), but lower odds of encephalopathy (OR 0.58, 95% CI 0.45-0.75, q<0.001), compared to white patients. Hispanic patients had higher odds of being diagnosed with headaches (OR 1.41, 95% CI 1.24-1.60, q<0.001) and chest pain (OR 1.50, 95% CI 1.35-1.67, q < 0.001), but lower odds of encephalopathy (OR 0.64, 95% CI 0.51-0.80, q<0.001).CONCLUSIONS:
Compared to white patients, patients from racial/ethnic minority groups had significantly different odds of developing potential PASC symptoms and conditions. Future research should examine the reasons for these differences.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Encefalopatias
/
COVID-19
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Gen Intern Med
Assunto da revista:
MEDICINA INTERNA
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos