Structure and Microbiological Activity of 1H-benzo[d]imidazole Derivatives.
Int J Mol Sci
; 24(4)2023 Feb 07.
Article
em En
| MEDLINE
| ID: mdl-36834732
ABSTRACT
Three new crystal structures of 1H-benzo[d]imidazole derivatives were determined. In the structures of these compounds, an identical system of hydrogen bonds, C(4), was observed. Solid-state NMR was applied for testing the quality of the obtained samples. All of these compounds were tested for in vitro antibacterial activity against Gram-positive bacteria and Gram-negative bacteria, as well as antifungal activity, by checking their selectivity. ADME calculations indicate that the compounds can be tested as potential drugs.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Antifúngicos
/
Nitroimidazóis
Idioma:
En
Revista:
Int J Mol Sci
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Polônia