Natural isoflavone formononetin inhibits IgE-mediated mast cell activation and allergic inflammation by increasing IgE receptor degradation.

Zhou, Zi-Wen; Ji, Kunmei; Zhu, Xue-Yan; Wu, Xin-Ying; Lin, Ruo-Tong; Xie, Chu-Chu; Cai, Ze-Lang; Chen, Jia-Jie

Zhou, Zi-Wen; Ji, Kunmei; Zhu, Xue-Yan; Wu, Xin-Ying; Lin, Ruo-Tong; Xie, Chu-Chu; Cai, Ze-Lang; Chen, Jia-Jie.

Afiliação

Zhou ZW; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Ji K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Zhu XY; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Wu XY; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Lin RT; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Xie CC; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Cai ZL; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.
Chen JJ; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shenzhen University Medical School, Shenzhen 518060, China. chenjj@szu.edu.cn.

Food Funct ; 14(6): 2857-2869, 2023 Mar 20.

Article em En | MEDLINE | ID: mdl-36880662

Assuntos

Anafilaxia; Isoflavonas; Camundongos; Animais; Receptores de IgE/genética; Receptores de IgE/metabolismo; Mastócitos; Transdução de Sinais; Anafilaxia/tratamento farmacológico; Imunoglobulina E/metabolismo; Isoflavonas/farmacologia; Isoflavonas/metabolismo; Inflamação/tratamento farmacológico; Inflamação/metabolismo; Degranulação Celular

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anafilaxia / Isoflavonas Limite: Animals Idioma: En Revista: Food Funct Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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