Therapy-Acquired Clonal Mutations in Thiopurine Drug-Response Genes Drive Majority of Early Relapses in Pediatric B-Cell Precursor Acute Lymphoblastic Leukemia.

Thakur, Rozy; Bhatia, Prateek; Singh, Minu; Sreedharanunni, Sreejesh; Sharma, Pankaj; Singh, Aditya; Trehan, Amita

Thakur, Rozy; Bhatia, Prateek; Singh, Minu; Sreedharanunni, Sreejesh; Sharma, Pankaj; Singh, Aditya; Trehan, Amita.

Afiliação

Thakur R; Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Bhatia P; Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Singh M; Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Sreedharanunni S; Department of Haematology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Sharma P; Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.
Singh A; Department of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USA.
Trehan A; Pediatric Hematology Oncology Unit, Department of Pediatrics, Advanced Pediatric Centre, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.

Diagnostics (Basel) ; 13(5)2023 Feb 25.

Article em En | MEDLINE | ID: mdl-36900028

Palavras-chave

B-ALL; deep sequencing; relapse; therapy-acquired

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Diagnostics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

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