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Social disadvantage during pregnancy: effects on gestational age and birthweight.
Luby, Joan L; England, Sarah K; Barch, Deanna M; Warner, Barbara B; Rogers, Cynthia; Smyser, Christopher D; Triplett, Regina; Arora, Jyoti; Smyser, Tara A; Slavich, George M; Zhao, Peinan; Stout, Molly; Herzog, Erik; Miller, J Philip.
Afiliação
  • Luby JL; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA. lubyj@wustl.edu.
  • England SK; Department of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Barch DM; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Warner BB; Department of Psychological & Brain Sciences, Washington University in St. Louis, St. Louis, MO, USA.
  • Rogers C; Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, USA.
  • Smyser CD; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Triplett R; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Arora J; Department of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
  • Smyser TA; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.
  • Slavich GM; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.
  • Zhao P; Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles, CA, USA.
  • Stout M; Department of Obstetrics and Gynecology, Center for Reproductive Health Sciences, Washington University School of Medicine, St. Louis, MO, USA.
  • Herzog E; Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.
  • Miller JP; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA.
J Perinatol ; 43(4): 477-483, 2023 04.
Article em En | MEDLINE | ID: mdl-36914799
ABSTRACT

OBJECTIVE:

Whether psychosocial adversity during pregnancy impacts fetal health outcomes at birth remains underexplored. This is a critical issue given significant social disadvantage and psychosocial stress faced by pregnant women worldwide. STUDY

DESIGN:

Measures of social disadvantage and psychological factors, and medical/reproductive and nutritional health status in pregnant women were obtained at each trimester. Using Structural Equation Modeling (SEM), we investigated the relationship of forms of adversity to each other and to infant gestational age, and birthweight.

RESULTS:

Among 399 singletons, Social Disadvantage significantly predicted gestational age (p = 0.003), and residual birthweight (p = 0.006). There was a 0.4 week decrease in gestational age and a 3% decrease in birthweight for each standard deviation increase in Social Disadvantage.

CONCLUSION:

Significant negative effects of social adversity on the developing fetus were found. Notably, these effects emerged despite good prenatal care and after accounting for maternal age and medical reproductive risk factors.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidado Pré-Natal / Recém-Nascido de Baixo Peso Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Newborn / Pregnancy Idioma: En Revista: J Perinatol Assunto da revista: PERINATOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cuidado Pré-Natal / Recém-Nascido de Baixo Peso Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Infant / Newborn / Pregnancy Idioma: En Revista: J Perinatol Assunto da revista: PERINATOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos