CAR-iNKT cells targeting clonal TCRVß chains as a precise strategy to treat T cell lymphoma.

Rowan, Aileen G; Ponnusamy, Kanagaraju; Ren, Hongwei; Taylor, Graham P; Cook, Lucy B M; Karadimitris, Anastasios

Rowan, Aileen G; Ponnusamy, Kanagaraju; Ren, Hongwei; Taylor, Graham P; Cook, Lucy B M; Karadimitris, Anastasios.

Afiliação

Rowan AG; Section of Virology, Department of Infectious Disease, Imperial College London, London, United Kingdom.
Ponnusamy K; Hugh and Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Ren H; Hugh and Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Taylor GP; Hugh and Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.
Cook LBM; Section of Virology, Department of Infectious Disease, Imperial College London, London, United Kingdom.
Karadimitris A; National Centre for Human Retrovirology, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, United Kingdom.

Front Immunol ; 14: 1118681, 2023.

Article em En | MEDLINE | ID: mdl-36936927

Assuntos

Vírus Linfotrópico T Tipo 1 Humano; Leucemia-Linfoma de Células T do Adulto; Linfoma de Células T Periférico; Linfoma de Células T; Células T Matadoras Naturais; Receptores de Antígenos Quiméricos; Adulto; Humanos; Receptores de Antígenos Quiméricos/genética; Receptores de Antígenos Quiméricos/metabolismo; Leucemia-Linfoma de Células T do Adulto/terapia; Linfoma de Células T/metabolismo

Palavras-chave

ATL; T cell lymphoma; T cell receptor; adult T cell leukaemia/lymphoma; chimeric antigen receptor (CAR) T-cells; human T cell leukaemia virus type-1; human T cell lymphotropic virus type-1 (HTLV-1); iNKT

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vírus Linfotrópico T Tipo 1 Humano / Leucemia-Linfoma de Células T do Adulto / Linfoma de Células T / Linfoma de Células T Periférico / Células T Matadoras Naturais / Receptores de Antígenos Quiméricos Limite: Adult / Humans Idioma: En Revista: Front Immunol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Reino Unido

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