Effectiveness and Safety of Energy-Based Devices for Acne Scars: A Network Meta-Analysis of Randomized Controlled Trials.
Facial Plast Surg Aesthet Med
; 25(6): 521-527, 2023.
Article
em En
| MEDLINE
| ID: mdl-36946785
ABSTRACT
Background:
Acne vulgaris is an inflammatory disease of the pilosebaceous unit in teenagers. Acne-induced inflammation leads to acne scarring. Scholars have discussed acne scar treatments; however, energy-based devices with satisfactory outcomes remain unidentified.Objective:
To measure quartile grading scale and visual analog scale (VAS) to study the difference between energy-based devices.Methods:
We included randomized controlled trials that evaluated patients with acne scars. The primary outcomes were the quartile grading scale and VAS scores. We used Confidence in Network Meta-Analysis to evaluate indirectness, imprecision, heterogeneity, and incoherence.Results:
A total of 26 studies met the inclusion criteria. The quartile grading scale results revealed that ablative fractional laser was significantly more effective than nonablative fractional laser (standard mean difference [SMD] 0.516, confidence interval [95% CI] 0.281-0.750) and radiofrequency treatment (SMD 0.941, 95% CI 0.540-1.342). Moreover, nonablative fractional laser was significantly more effective than radiofrequency treatment (SMD 0.426, 95% CI 0.049-0.802). No significant difference in VAS score was found among the devices.Conclusion:
Ablative fractional laser is an effective treatment for acne scars although it is associated with more pain.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatriz
/
Acne Vulgar
Tipo de estudo:
Clinical_trials
/
Systematic_reviews
Limite:
Adolescent
/
Humans
Idioma:
En
Revista:
Facial Plast Surg Aesthet Med
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Taiwan