Bulk and single-cell transcriptome analyses of islet tissue unravel gene signatures associated with pyroptosis and immune infiltration in type 2 diabetes.

Song, Yaxian; He, Chen; Jiang, Yan; Yang, Mengshi; Xu, Zhao; Yuan, Lingyan; Zhang, Wenhua; Xu, Yushan

Song, Yaxian; He, Chen; Jiang, Yan; Yang, Mengshi; Xu, Zhao; Yuan, Lingyan; Zhang, Wenhua; Xu, Yushan.

Afiliação

Song Y; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
He C; Department of Geriatric Medicine, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Jiang Y; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yang M; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Xu Z; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Yuan L; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Zhang W; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.
Xu Y; Department of Endocrinology, Yunnan Province Clinical Medical Center for Endocrine and Metabolic Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China.

Front Endocrinol (Lausanne) ; 14: 1132194, 2023.

Article em En | MEDLINE | ID: mdl-36967805

Assuntos

Diabetes Mellitus Tipo 2; Piroptose; Humanos; Piroptose/genética; Diabetes Mellitus Tipo 2/genética; Modelos Estatísticos; Análise da Expressão Gênica de Célula Única; Prognóstico

Palavras-chave

differentially expressed gene; immune infiltration; pyroptosis; single-cell RNA; type 2 diabetes

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diabetes Mellitus Tipo 2 / Piroptose Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Front Endocrinol (Lausanne) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google