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VMAP: Vaginal Microbiome Atlas During Pregnancy.
Parraga-Leo, Antonio; Oskotsky, Tomiko T; Oskotsky, Boris; Wibrand, Camilla; Roldan, Alennie; Tang, Alice; Ha, Connie W Y; Wong, Ronald J; Minot, Samuel S; Andreoletti, Gaia; Kosti, Idit; Theis, Kevin R; Ng, Sherrianne; Lee, Yun S; Diaz-Gimeno, Patricia; Bennett, Phillip R; MacIntyre, David A; Lynch, Susan V; Romero, Roberto; Tarca, Adi L; Stevenson, David K; Aghaeepour, Nima; Golob, Jonathan; Sirota, Marina.
Afiliação
  • Parraga-Leo A; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Oskotsky TT; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • Oskotsky B; March of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA USA.
  • Wibrand C; Department of Pediatrics, Obstetrics and Gynaecology, Universidad de Valencia, Valencia, Spain.
  • Roldan A; Instituto de Investigación Sanitaria La Fe (IIS La Fe), IVI Foundation, Valencia, Spain.
  • Tang A; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Ha CWY; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • Wong RJ; March of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA USA.
  • Minot SS; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Andreoletti G; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • Kosti I; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Theis KR; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • Ng S; March of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA USA.
  • Lee YS; Department of Pediatrics, Obstetrics and Gynaecology, Universidad de Valencia, Valencia, Spain.
  • Diaz-Gimeno P; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Bennett PR; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • MacIntyre DA; March of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA USA.
  • Lynch SV; Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA. USA.
  • Romero R; Department of Pediatrics. University of California San Francisco, San Francisco, CA. USA.
  • Tarca AL; March of Dimes Prematurity Research Center at the University of California San Francisco, San Francisco, CA USA.
  • Stevenson DK; Benioff Center for Microbiome Medicine, Department of Medicine, University of California, San Francisco, CA. USA.
  • Aghaeepour N; Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, California. USA.
  • Golob J; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA. USA.
  • Sirota M; Data Core, Fred Hutchinson Cancer Center. Seattle, WA. USA.
medRxiv ; 2023 Apr 05.
Article em En | MEDLINE | ID: mdl-36993193
ABSTRACT
The vaginal microbiome has been shown to be associated with pregnancy outcomes including preterm birth (PTB) risk. Here we present VMAP Vaginal Microbiome Atlas during Pregnancy (http//vmapapp.org), an application to visualize features of 3,909 vaginal microbiome samples of 1,416 pregnant individuals from 11 studies, aggregated from raw public and newly generated sequences via an open-source tool, MaLiAmPi. Our visualization tool (http//vmapapp.org) includes microbial features such as various measures of diversity, VALENCIA community state types (CST), and composition (via phylotypes and taxonomy). This work serves as a resource for the research community to further analyze and visualize vaginal microbiome data in order to better understand both healthy term pregnancies and those associated with adverse outcomes.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: MedRxiv Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: MedRxiv Ano de publicação: 2023 Tipo de documento: Article