USP8 inhibition regulates autophagy flux and controls <i>Salmonella</i> infection.

Santelices, John; Ou, Mark; Maegawa, Gustavo H B; Hercik, Kamil; Edelmann, Mariola J

USP8 inhibition regulates autophagy flux and controls Salmonella infection.

Santelices, John; Ou, Mark; Maegawa, Gustavo H B; Hercik, Kamil; Edelmann, Mariola J.

Afiliação

Santelices J; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Ou M; Department of Microbiology and Cell Science, Institute of Food and Agricultural Sciences, University of Florida, Gainesville, FL, United States.
Maegawa GHB; Department of Pediatrics and Genetics, Columbia University Irving Medical Center, Vagelos Physicians and Surgeons College of Medicine, New York, NY, United States.
Hercik K; Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague, Czechia.
Edelmann MJ; Department of Molecular Pathology and Biology, Faculty of Military Health Sciences, University of Defense, Hradec Kralove, Czechia.

Front Cell Infect Microbiol ; 13: 1070271, 2023.

Article em En | MEDLINE | ID: mdl-37026055

Assuntos

Infecções por Salmonella; Humanos; Salmonella typhimurium/metabolismo; Autofagia; Ubiquitinação; Enzimas Desubiquitinantes/metabolismo; Endopeptidases/genética; Ubiquitina Tiolesterase/genética; Ubiquitina Tiolesterase/metabolismo; Complexos Endossomais de Distribuição Requeridos para Transporte/genética

Palavras-chave

Salmonella; USP8; autophagy; chemical proteomics; deubiquitinases; deubiquitinating enzymes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Infecções por Salmonella Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Front Cell Infect Microbiol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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