Netrin-1 inducing antiapoptotic effect of acute myeloid leukemia cells in a concentration-dependent manner through the Unc-5 netrin receptor B-focal adhesion kinase axis.

Zhang, Kainan; An, Xizhou; Zhu, Yao; Huang, Lan; Yao, Xinyuan; Zeng, Xing; Liang, Shaoyan; Yu, Jie

Zhang, Kainan; An, Xizhou; Zhu, Yao; Huang, Lan; Yao, Xinyuan; Zeng, Xing; Liang, Shaoyan; Yu, Jie.

Afiliação

Zhang K; Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
An X; Pediatric research institute, Children's Hospital of Chongqing Medical University, Chongqing, China.
Zhu Y; Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Huang L; Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Yao X; Pediatric research institute, Children's Hospital of Chongqing Medical University, Chongqing, China.
Zeng X; Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.
Liang S; Pediatric research institute, Children's Hospital of Chongqing Medical University, Chongqing, China.
Yu J; Department of Hematology and Oncology, Children's Hospital of Chongqing Medical University; National Clinical Research Center for Child Health and Disorders; Ministry of Education Key Laboratory of Child Development and Disorders; Chongqing Key Laboratory of Pediatrics, Chongqing, China.

Cancer Biol Ther ; 24(1): 2200705, 2023 12 31.

Article em En | MEDLINE | ID: mdl-37038247

Assuntos

Leucemia Mieloide Aguda; Netrina-1; Proteínas Proto-Oncogênicas c-akt; Criança; Humanos; Proteína-Tirosina Quinases de Adesão Focal/metabolismo; Receptores de Netrina; Proteínas Proto-Oncogênicas c-akt/metabolismo

Palavras-chave

FAK-Akt; Netrin-1; UNC5B; acute myeloid leukemia; apoptosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Proteínas Proto-Oncogênicas c-akt / Netrina-1 Tipo de estudo: Prognostic_studies Limite: Child / Humans Idioma: En Revista: Cancer Biol Ther Assunto da revista: NEOPLASIAS / TERAPEUTICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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