Quorum sensing-based metabolic engineering of the precursor supply in Streptomyces coelicolor to improve heterologous production of neoaureothin.

Kim, Do-Kyung; Gu, Boncheol; Kim, Duck Gyun; Oh, Min-Kyu

Kim, Do-Kyung; Gu, Boncheol; Kim, Duck Gyun; Oh, Min-Kyu.

Afiliação

Kim DK; Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.
Gu B; Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.
Kim DG; Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.
Oh MK; Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.

Biotechnol Bioeng ; 120(7): 2039-2044, 2023 07.

Article em En | MEDLINE | ID: mdl-37042226

Assuntos

Policetídeos; Streptomyces coelicolor; Streptomyces; Streptomyces coelicolor/genética; Streptomyces coelicolor/metabolismo; Engenharia Metabólica; Percepção de Quorum/genética; Streptomyces/genética; Policetídeos/metabolismo

Palavras-chave

Streptomyces; heterologous production; metabolic engineering; neoaureothin; polyketide; quorum sensing

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Streptomyces / Streptomyces coelicolor / Policetídeos Idioma: En Revista: Biotechnol Bioeng Ano de publicação: 2023 Tipo de documento: Article

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