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Discovery of E2730, a novel selective uncompetitive GAT1 inhibitor, as a candidate for anti-seizure medication.
Fukushima, Kazuyuki; Higashiyama, Hiroyuki; Kazuta, Yuji; Hashimoto, Keisuke; Watanabe, Naoto; Furuya, Yoshiaki; Ito, Yoshimasa; Wu, Ting; Kosasa, Takashi; Talos, Delia M; Song, Yeri; Roberts, Nicholas S; Jensen, Frances E; Hanada, Takahisa; Ido, Katsutoshi.
Afiliação
  • Fukushima K; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Higashiyama H; Neurology Business Group, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Kazuta Y; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Hashimoto K; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Watanabe N; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Furuya Y; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Ito Y; Neurology Business Group, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Wu T; Alzheimer's Disease and Brain Health, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Kosasa T; Neurology Business Group, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Talos DM; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Song Y; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Roberts NS; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Jensen FE; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Hanada T; Deep Human Biology Learning, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
  • Ido K; Neurology Business Group, Eisai Co., Ltd., Tsukuba, Ibaraki, Japan.
Epilepsia Open ; 8(3): 834-845, 2023 09.
Article em En | MEDLINE | ID: mdl-37052238
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epilepsia / Proteínas da Membrana Plasmática de Transporte de GABA / Anticonvulsivantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Epilepsia Open Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Epilepsia / Proteínas da Membrana Plasmática de Transporte de GABA / Anticonvulsivantes Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Epilepsia Open Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão