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Metabolomic Profiling and Drug Interaction Characterization Reveal Riboflavin As a Breast Cancer Resistance Protein-Specific Endogenous Biomarker That Demonstrates Prediction of Transporter Activity In Vivo.
Zhang, Yueping; Shipkova, Petia A; Warrack, Bethanne M; Nelson, David M; Wang, Linna; Huo, Runlan; Chen, Jian; Panfen, Erika; Chen, Xue-Qing; Fancher, R Marcus; Ruan, Qian; Christopher, Lisa J; Xue, Yongjun; Sinz, Michael; Shen, Hong.
Afiliação
  • Zhang Y; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Shipkova PA; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Warrack BM; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Nelson DM; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Wang L; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Huo R; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Chen J; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Panfen E; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Chen XQ; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Fancher RM; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Ruan Q; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Christopher LJ; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Xue Y; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Sinz M; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
  • Shen H; Departments of Drug Metabolism and Pharmacokinetics (Y.Z., E.P., R.M.F., M.S., H.S.), Bioanalytical Research (P.A.S., B.M.W.), Translational Development (D.M.N.), Nonclinical Disposition and Bioanalysis (L.W., R.H., J.C., Q.R., L.J.C., Y.X.), and Discovery Pharmaceutics (X.-Q.C.), Bristol Myers Squi
Drug Metab Dispos ; 51(7): 851-861, 2023 Jul.
Article em En | MEDLINE | ID: mdl-37055191
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Neoplasias da Mama Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Neoplasias da Mama Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Female / Humans Idioma: En Revista: Drug Metab Dispos Assunto da revista: FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article