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PPRX-1701, a nanoparticle formulation of 6'-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models.
Zdioruk, Mykola; Jimenez-Macias, Jorge-Luis; Nowicki, Michal Oskar; Manz, Katherine E; Pennell, Kurt D; Koch, Marilin S; Finkelberg, Tomer; Wu, Bin; Boucher, Paul; Takeda, Yuji; Li, Weiyi; Piranlioglu, Raziye; Ling, Alexander L; Chiocca, E Antonio; Lawler, Sean E.
Afiliação
  • Zdioruk M; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Jimenez-Macias JL; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Pathology and Laboratory Medicine, Department of Neurosurgery, Legorreta Cancer Center, Brown University, Providence, RI 02903, USA.
  • Nowicki MO; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Manz KE; School of Engineering, Brown University, Providence, RI 02912, USA.
  • Pennell KD; School of Engineering, Brown University, Providence, RI 02912, USA.
  • Koch MS; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Finkelberg T; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Wu B; Phosphorex, Inc, Hopkinton, MA 01748, USA; Cytodigm, Inc., Hopkinton, MA 01748, USA.
  • Boucher P; Phosphorex, Inc, Hopkinton, MA 01748, USA.
  • Takeda Y; Phosphorex, Inc, Hopkinton, MA 01748, USA.
  • Li W; Phosphorex, Inc, Hopkinton, MA 01748, USA.
  • Piranlioglu R; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Ling AL; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Chiocca EA; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
  • Lawler SE; Harvey Cushing Neurooncology Laboratories, Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Department of Pathology and Laboratory Medicine, Department of Neurosurgery, Legorreta Cancer Center, Brown University, Providence, RI 02903, USA. Ele
Cell Rep Med ; 4(5): 101019, 2023 05 16.
Article em En | MEDLINE | ID: mdl-37060903
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma Limite: Animals Idioma: En Revista: Cell Rep Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Glioblastoma Limite: Animals Idioma: En Revista: Cell Rep Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos