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Exposure to microbial products followed by loss of Tet2 promotes myelodysplastic syndrome via remodeling HSCs.
Yokomizo-Nakano, Takako; Hamashima, Ai; Kubota, Sho; Bai, Jie; Sorin, Supannika; Sun, Yuqi; Kikuchi, Kenta; Iimori, Mihoko; Morii, Mariko; Kanai, Akinori; Iwama, Atsushi; Huang, Gang; Kurotaki, Daisuke; Takizawa, Hitoshi; Matsui, Hirotaka; Sashida, Goro.
Afiliação
  • Yokomizo-Nakano T; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Hamashima A; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo , Tokyo, Japan.
  • Kubota S; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Bai J; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Sorin S; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Sun Y; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Kikuchi K; Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
  • Iimori M; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Morii M; Laboratory of Chromatin Organization in Immune Cell Development, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Kanai A; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Iwama A; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Huang G; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Chiba, Japan.
  • Kurotaki D; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo , Tokyo, Japan.
  • Takizawa H; Department of Cell Systems & Anatomy, Department of Pathology and Laboratory Medicine, UT Health San Antonio, Joe R. and Teresa Lozano Long School of Medicine, Mays Cancer Center at UT Health San Antonio, San Antonio, TX, USA.
  • Matsui H; Laboratory of Chromatin Organization in Immune Cell Development, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
  • Sashida G; Laboratory of Stem Cell Stress, International Research Center for Medical Sciences, Kumamoto University , Kumamoto, Japan.
J Exp Med ; 220(7)2023 07 03.
Article em En | MEDLINE | ID: mdl-37071125

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Dioxigenases Limite: Humans Idioma: En Revista: J Exp Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Dioxigenases Limite: Humans Idioma: En Revista: J Exp Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão