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Discovery of CVN636: A Highly Potent, Selective, and CNS Penetrant mGluR7 Allosteric Agonist.
Dickson, Louise; Teall, Martin; Chevalier, Elodie; Cheung, Toni; Liwicki, Gemma M; Mack, Stephen; Stephenson, Anne; White, Kathryn; Fosbeary, Richard; Harrison, David C; Brice, Nicola L; Doyle, Kevin; Ciccocioppo, Roberto; Wu, Chaobo; Almond, Sarah; Patel, Toshal R; Mitchell, Philip; Barnes, Matt; Ayscough, Andrew P; Dawson, Lee A; Carlton, Mark; Bürli, Roland W.
Afiliação
  • Dickson L; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Teall M; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Chevalier E; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Cheung T; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Liwicki GM; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Mack S; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Stephenson A; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • White K; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Fosbeary R; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Harrison DC; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Brice NL; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Doyle K; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Ciccocioppo R; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Wu C; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Almond S; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Patel TR; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Mitchell P; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Barnes M; Cerevance Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Ayscough AP; School of Pharmacy, Pharmacology Unit, University of Camerino, Camerino 62032, Italy.
  • Dawson LA; WuXi Apptec Limited, 288 Fute Zhong Road, Waigaoqiao Free Trade Zone, Shanghai 200131, China.
  • Carlton M; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
  • Bürli RW; Takeda Cambridge Limited, 418 Cambridge Science Park, Cambridge CB4 0PZ, U.K.
ACS Med Chem Lett ; 14(4): 442-449, 2023 Apr 13.
Article em En | MEDLINE | ID: mdl-37077399
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2023 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Med Chem Lett Ano de publicação: 2023 Tipo de documento: Article