FGFR2 mutations promote endometrial cancer progression through dual engagement of EGFR and Notch signalling pathways.

Dixit, Garima; Gonzalez-Bosquet, Jesus; Skurski, Joseph; Devor, Eric J; Dickerson, Erin B; Nothnick, Warren B; Issuree, Priya D; Leslie, Kimberly K; Maretzky, Thorsten

Dixit, Garima; Gonzalez-Bosquet, Jesus; Skurski, Joseph; Devor, Eric J; Dickerson, Erin B; Nothnick, Warren B; Issuree, Priya D; Leslie, Kimberly K; Maretzky, Thorsten.

Afiliação

Dixit G; Inflammation Program, University of Iowa, Iowa City, Iowa, USA.
Gonzalez-Bosquet J; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Skurski J; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa, USA.
Devor EJ; Holden Comprehensive Cancer Center, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
Dickerson EB; Inflammation Program, University of Iowa, Iowa City, Iowa, USA.
Nothnick WB; Department of Internal Medicine, University of Iowa, Iowa City, Iowa, USA.
Issuree PD; Immunology Graduate Program, University of Iowa, Iowa City, Iowa, USA.
Leslie KK; Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa, USA.
Maretzky T; Holden Comprehensive Cancer Center, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.

Clin Transl Med ; 13(5): e1223, 2023 05.

Article em En | MEDLINE | ID: mdl-37165578

Assuntos

Neoplasias do Endométrio; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos; Feminino; Humanos; Camundongos; Animais; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/genética; Receptor Tipo 2 de Fator de Crescimento de Fibroblastos/metabolismo; Receptores ErbB/genética; Receptores ErbB/metabolismo; Transdução de Sinais/genética; Neoplasias do Endométrio/genética; Neoplasias do Endométrio/patologia; Mutação/genética

Palavras-chave

Notch; a disintegrin and metalloprotease 10; a disintegrin and metalloprotease 17; endometrial cancer; epidermal growth factor receptor; fibroblast growth factor receptor 2

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias do Endométrio / Receptor Tipo 2 de Fator de Crescimento de Fibroblastos Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Clin Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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