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Methylmercury directly modifies the 105th cysteine residue in oncostatin M to promote binding to tumor necrosis factor receptor 3 and inhibit cell growth.
Toyama, Takashi; Xu, Sidi; Kanemitsu, Yoshitomi; Hasegawa, Takashi; Noguchi, Takuya; Lee, Jin-Yong; Matsuzawa, Atsushi; Naganuma, Akira; Hwang, Gi-Wook.
Afiliação
  • Toyama T; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Xu S; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Kanemitsu Y; Clinical and Translational Research Center, Niigata University Medical and Dental Hospital, 2-5274 Gakkochodori, Chuo-ku, Niigata, Niigata, 980-8574, Japan.
  • Hasegawa T; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Noguchi T; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Lee JY; Laboratory of Pharmaceutical Health Sciences, School of Pharmacy, Aichi Gakuin University, 1-100 Kusumoto-cho, Chikusa-ku, Nagoya, 951-8514, Japan.
  • Matsuzawa A; Laboratory of Health Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Naganuma A; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan.
  • Hwang GW; Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan. hwang@tohoku-mpu.ac.jp.
Arch Toxicol ; 97(7): 1887-1897, 2023 07.
Article em En | MEDLINE | ID: mdl-37193757

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Compostos de Metilmercúrio Idioma: En Revista: Arch Toxicol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cisteína / Compostos de Metilmercúrio Idioma: En Revista: Arch Toxicol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Japão