Alterations in pulmonary vasomotor modulators post aerobic exercise training in non-alcoholic fatty liver disease.
Respir Physiol Neurobiol
; 314: 104089, 2023 08.
Article
em En
| MEDLINE
| ID: mdl-37269888
ABSTRACT
This study investigated the impact of exercise training on major pulmonary vasomotor mediators and receptors including endothelial nitric oxide synthase (eNOS) inducible NOS (iNOS), endothelin-1 (ET-1), ET-1 receptors A (ETA) and-B (ETB) in high-fat-high-carbohydrate (HFHC) induced non-alcoholic fatty liver disease (NAFLD). NAFLD increased iNOS, ET-1 and ETA (p < 0.05), but not ETB (p > 0.05). Exercise attenuated iNOS, ET-1 and ETA (p < 0.05)., but not ETB (p > 0.05) and eNOS (p > 0.05). Exercise training is beneficial for pulmonary vasculature in NAFLD.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Óxido Nítrico Sintase
/
Hepatopatia Gordurosa não Alcoólica
Limite:
Humans
Idioma:
En
Revista:
Respir Physiol Neurobiol
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Estados Unidos