Inhibition of Erb-B2 Receptor Tyrosine Kinase 3 and Associated Regulatory Pathways Potently Impairs Malignant Peripheral Nerve Sheath Tumor Proliferation and Survival.

Black, Laurel E; Longo, Jody F; Anderson, Joshua C; Carroll, Steven L

Black, Laurel E; Longo, Jody F; Anderson, Joshua C; Carroll, Steven L.

Afiliação

Black LE; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina.
Longo JF; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina.
Anderson JC; Department of Radiation Oncology, University of Alabama at Birmingham, Birmingham, Alabama.
Carroll SL; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address: carrolst@musc.edu.

Am J Pathol ; 193(9): 1298-1318, 2023 09.

Article em En | MEDLINE | ID: mdl-37328102

Assuntos

Leucemia; Neoplasias de Bainha Neural; Neurofibrossarcoma; Humanos; Camundongos; Animais; Receptor ErbB-2/metabolismo; Receptor ErbB-2/uso terapêutico; Neoplasias de Bainha Neural/tratamento farmacológico; Neoplasias de Bainha Neural/genética; Neoplasias de Bainha Neural/metabolismo; Calmodulina/metabolismo; Calmodulina/farmacologia; Calmodulina/uso terapêutico; Sirolimo/farmacologia; Proliferação de Células; Serina-Treonina Quinases TOR/metabolismo; Proteínas Quinases Ativadas por Mitógeno/metabolismo; Linhagem Celular Tumoral; Mamíferos/metabolismo

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Neurofibrossarcoma / Neoplasias de Bainha Neural Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Am J Pathol Ano de publicação: 2023 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google