Ceratonia siliqua pods (Carob) methanol extract alleviates doxorubicin-induced nephrotoxicity via antioxidant, anti-inflammatory and anti-apoptotic pathways in rats.

Atta, Attia H; Atta, Shimaa A; Khattab, Marwa S; El-Aziz, Tamer H Abd; Mouneir, Samar M; Ibrahim, Marwa A; Nasr, Soad M; Emam, Shimaa R

Atta, Attia H; Atta, Shimaa A; Khattab, Marwa S; El-Aziz, Tamer H Abd; Mouneir, Samar M; Ibrahim, Marwa A; Nasr, Soad M; Emam, Shimaa R.

Afiliação

Atta AH; Pharmacology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 1211, Egypt. attaattia52@cu.edu.eg.
Atta SA; Immunology Department, Theodor Belharz Research Institute, Giza, 12411, Egypt.
Khattab MS; Pathology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 1211, Egypt.
El-Aziz THA; Department of Parasitology and Animal Diseases, National Research Centre, 33 Bohouth St, DokkiGiza, 12622, Egypt.
Mouneir SM; Pharmacology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 1211, Egypt.
Ibrahim MA; Biochemistry and Molecular Biology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 1211, Egypt.
Nasr SM; Department of Parasitology and Animal Diseases, National Research Centre, 33 Bohouth St, DokkiGiza, 12622, Egypt.
Emam SR; Pharmacology Department, Faculty of Veterinary Medicine, Cairo University, Giza, 1211, Egypt.

Environ Sci Pollut Res Int ; 30(35): 83421-83438, 2023 Jul.

Article em En | MEDLINE | ID: mdl-37341944

Assuntos

Antioxidantes; Fabaceae; Ratos; Animais; Camundongos; Antioxidantes/farmacologia; Antioxidantes/metabolismo; Interleucina-10/metabolismo; Caspase 9/metabolismo; Caspase 9/farmacologia; Metanol; Ratos Wistar; Fator de Necrose Tumoral alfa/metabolismo; Interleucina-6/metabolismo; Ciclo-Oxigenase 2/metabolismo; Proteína X Associada a bcl-2/metabolismo; Doxorrubicina/toxicidade; Rim; Anti-Inflamatórios/farmacologia; Estresse Oxidativo; Fabaceae/metabolismo; Fator de Crescimento Transformador beta/metabolismo; Apoptose

Palavras-chave

Anti-Inflammatory; Anti-apoptotic; Antioxidant; Carob; Ceratonia siliqua; Doxorubicin; Nephrotoxicity; Phytochemistry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fabaceae / Antioxidantes Limite: Animals Idioma: En Revista: Environ Sci Pollut Res Int Assunto da revista: SAUDE AMBIENTAL / TOXICOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Egito

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