Onco-condensates: formation, multi-component organization, and biological functions.

Xu, Chenxi; Kim, Arum; Corbin, Joshua M; Wang, Gang Greg

Xu, Chenxi; Kim, Arum; Corbin, Joshua M; Wang, Gang Greg.

Afiliação

Xu C; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Kim A; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Corbin JM; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Wang GG; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA; Department of Pharmacology, University of Nor

Trends Cancer ; 9(9): 738-751, 2023 09.

Article em En | MEDLINE | ID: mdl-37349246

Assuntos

Carcinogênese; Transformação Celular Neoplásica; Humanos; Cromatina/genética

Palavras-chave

biomolecular condensation; cancer; disease; intrinsically disordered region (IDR); onco-condensate; phase separation; small molecule; therapeutic

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Carcinogênese Limite: Humans Idioma: En Revista: Trends Cancer Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos

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