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Cataract-causing Y204X mutation of crystallin protein CRYßB1 promotes its C-terminal degradation and higher-order oligomerization.
Jing, Xuping; Zhu, Mingwei; Lu, Xiaoyun; Wei, Ping; Shi, Lingyu; Zhang, Bu-Yu; Xu, Yi; Tang, Ya-Ping; Xiang, Dao-Man; Gong, Peng.
Afiliação
  • Jing X; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China; Key L
  • Zhu M; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Lu X; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Wei P; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Shi L; Department of Ophthalmology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Zhang BY; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China; University of Chinese Academy of Sciences, Beijing, China.
  • Xu Y; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China.
  • Tang YP; Joint Laboratory for Translational Precision Medicine, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China; Joint Laboratory for Translational Precision Medicine, Wuhan Institute of Virology, Chinese Academy of Sciences, Wuhan, Hubei, China; Goung
  • Xiang DM; Department of Ophthalmology, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address: xiangdm35@126.com.
  • Gong P; Key Laboratory of Special Pathogens and Biosafety, Wuhan Institute of Virology, Center for Biosafety Mega-Science, Chinese Academy of Sciences, Wuhan, Hubei, China. Electronic address: gongpeng@wh.iov.cn.
J Biol Chem ; 299(8): 104953, 2023 08.
Article em En | MEDLINE | ID: mdl-37356717

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Catarata / Cristalinas / Cristalino Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Catarata / Cristalinas / Cristalino Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Biol Chem Ano de publicação: 2023 Tipo de documento: Article