Gut-on-a-Chip Research for Drug Development: Implications of Chip Design on Preclinical Oral Bioavailability or Intestinal Disease Studies.

Donkers, Joanne M; van der Vaart, Jamie I; van de Steeg, Evita

Donkers, Joanne M; van der Vaart, Jamie I; van de Steeg, Evita.

Afiliação

Donkers JM; Department of Metabolic Health Research, TNO, Sylviusweg 71, 2333 BE Leiden, The Netherlands.
van der Vaart JI; Department of Metabolic Health Research, TNO, Sylviusweg 71, 2333 BE Leiden, The Netherlands.
van de Steeg E; Division of Endocrinology, Department of Medicine, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands.

Biomimetics (Basel) ; 8(2)2023 May 28.

Article em En | MEDLINE | ID: mdl-37366821

Palavras-chave

ADME; IBD; drug development; ex vivo; gut-on-a-chip; in vitro; intestine; microbiome; oral bioavailability; organ-on-a-chip

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Biomimetics (Basel) Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

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