Genetically programmed retinoic acid deficiency during gastrulation phenocopies most known developmental defects due to acute prenatal alcohol exposure in FASD.

Petrelli, B; Oztürk, A; Pind, M; Ayele, H; Fainsod, A; Hicks, G G

Petrelli, B; Oztürk, A; Pind, M; Ayele, H; Fainsod, A; Hicks, G G.

Afiliação

Petrelli B; Department of Biochemistry and Medical Genetics, Regenerative Medicine Program, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Oztürk A; Department of Biochemistry and Medical Genetics, Regenerative Medicine Program, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Pind M; Department of Biochemistry and Medical Genetics, Regenerative Medicine Program, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Ayele H; Department of Biochemistry and Medical Genetics, Regenerative Medicine Program, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.
Fainsod A; Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Hicks GG; Department of Biochemistry and Medical Genetics, Regenerative Medicine Program, Faculty of Medicine, University of Manitoba, Winnipeg, MB, Canada.

Front Cell Dev Biol ; 11: 1208279, 2023.

Article em En | MEDLINE | ID: mdl-37397253

Palavras-chave

craniofacial malformations; fetal alcohol spectrum disorder (FASD); gastrulation; malocclusion; prenatal alcohol exposure (PAE); retinoic acid; vitamin A deficiency

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Front Cell Dev Biol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Canadá

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