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Combined CDK4/6 and ERK1/2 Inhibition Enhances Antitumor Activity in NF1-Associated Plexiform Neurofibroma.
Flint, Alyssa C; Mitchell, Dana K; Angus, Steven P; Smith, Abbi E; Bessler, Waylan; Jiang, Li; Mang, Henry; Li, Xiaohong; Lu, Qingbo; Rodriguez, Brooke; Sandusky, George E; Masters, Andi R; Zhang, Chi; Dang, Pengtao; Koenig, Jenna; Johnson, Gary L; Shen, Weihua; Liu, Jiangang; Aggarwal, Amit; Donoho, Gregory P; Willard, Melinda D; Bhagwat, Shripad V; Clapp, D Wade; Rhodes, Steven D.
Afiliação
  • Flint AC; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Mitchell DK; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Angus SP; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Smith AE; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
  • Bessler W; Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indianapolis, Indiana.
  • Jiang L; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Mang H; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Li X; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Lu Q; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Rodriguez B; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Sandusky GE; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Masters AR; Department of Pediatrics, Herman B Wells Center for Pediatric Research, Indiana University School of Medicine, Indianapolis, Indiana.
  • Zhang C; Department of Pathology, Indiana University School of Medicine, Indianapolis, Indiana.
  • Dang P; Clinical Pharmacology Analytical Core, Indiana University School of Medicine, Indianapolis, Indiana.
  • Koenig J; Center for Computational Biology and Bioinformatics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.
  • Johnson GL; Center for Computational Biology and Bioinformatics and Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana.
  • Shen W; Medical Scientist Training Program, Indiana University School of Medicine, Indianapolis, Indiana.
  • Liu J; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
  • Aggarwal A; UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
  • Donoho GP; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Willard MD; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Bhagwat SV; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Clapp DW; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
  • Rhodes SD; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana.
Clin Cancer Res ; 29(17): 3438-3456, 2023 09 01.
Article em En | MEDLINE | ID: mdl-37406085
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromatose 1 / Neurofibroma Plexiforme / Neoplasias de Bainha Neural / Neurofibroma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neurofibromatose 1 / Neurofibroma Plexiforme / Neoplasias de Bainha Neural / Neurofibroma Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Clin Cancer Res Assunto da revista: NEOPLASIAS Ano de publicação: 2023 Tipo de documento: Article