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Proprotein convertase subtilisin/kexin type 9 targets megalin in the kidney proximal tubule and aggravates proteinuria in nephrotic syndrome.
Skeby, Cecilie K; Hummelgaard, Sandra; Gustafsen, Camilla; Petrillo, Federica; Frederiksen, Kathrine P; Olsen, Ditte; Kristensen, Tilde; Ivarsen, Per; Madsen, Peder; Christensen, Erik I; Nielsen, Rikke; Birn, Henrik; Glerup, Simon; Weyer, Kathrin.
Afiliação
  • Skeby CK; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Hummelgaard S; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Gustafsen C; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Draupnir Bio, INCUBA Skejby, Aarhus, Denmark.
  • Petrillo F; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Frederiksen KP; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Olsen D; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Draupnir Bio, INCUBA Skejby, Aarhus, Denmark.
  • Kristensen T; Department of Internal Medicine, Renal Unit, Regional Hospital Viborg, Viborg, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark.
  • Ivarsen P; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
  • Madsen P; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Draupnir Bio, INCUBA Skejby, Aarhus, Denmark.
  • Christensen EI; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Nielsen R; Department of Biomedicine, Aarhus University, Aarhus, Denmark.
  • Birn H; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark; Department of Renal Medicine, Aarhus University Hospital, Aarhus, Denmark.
  • Glerup S; Department of Biomedicine, Aarhus University, Aarhus, Denmark; Draupnir Bio, INCUBA Skejby, Aarhus, Denmark.
  • Weyer K; Department of Biomedicine, Aarhus University, Aarhus, Denmark. Electronic address: kw@biomed.au.dk.
Kidney Int ; 104(4): 754-768, 2023 10.
Article em En | MEDLINE | ID: mdl-37406929
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Insuficiência Renal Crônica / Síndrome Nefrótica Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Cardiovasculares / Insuficiência Renal Crônica / Síndrome Nefrótica Limite: Animals / Humans Idioma: En Revista: Kidney Int Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca