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Improved antibody pharmacokinetics by disruption of contiguous positive surface potential and charge reduction using alternate human framework.
Ollier, Romain; Fuchs, Aline; Gauye, Florence; Piorkowska, Katarzyna; Menant, Sébastien; Ratnam, Monisha; Montanari, Paolo; Guilhot, Florence; Phillipe, Didier; Audrain, Mickael; Egesipe, Anne-Laure; Névoltris, Damien; Seredenina, Tamara; Pfeifer, Andrea; Kosco-Vilbois, Marie; Afroz, Tariq.
Afiliação
  • Ollier R; Research, AC Immune SA, Lausanne, Switzerland.
  • Fuchs A; Research, AC Immune SA, Lausanne, Switzerland.
  • Gauye F; Research, AC Immune SA, Lausanne, Switzerland.
  • Piorkowska K; Research, AC Immune SA, Lausanne, Switzerland.
  • Menant S; Research, AC Immune SA, Lausanne, Switzerland.
  • Ratnam M; Research, AC Immune SA, Lausanne, Switzerland.
  • Montanari P; Research, AC Immune SA, Lausanne, Switzerland.
  • Guilhot F; Research, AC Immune SA, Lausanne, Switzerland.
  • Phillipe D; Research, AC Immune SA, Lausanne, Switzerland.
  • Audrain M; Research, AC Immune SA, Lausanne, Switzerland.
  • Egesipe AL; Research, AC Immune SA, Lausanne, Switzerland.
  • Névoltris D; Research, AC Immune SA, Lausanne, Switzerland.
  • Seredenina T; Research, AC Immune SA, Lausanne, Switzerland.
  • Pfeifer A; Research, AC Immune SA, Lausanne, Switzerland.
  • Kosco-Vilbois M; Research, AC Immune SA, Lausanne, Switzerland.
  • Afroz T; Research, AC Immune SA, Lausanne, Switzerland.
MAbs ; 15(1): 2232087, 2023.
Article em En | MEDLINE | ID: mdl-37408314
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Fc / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores Fc / Anticorpos Monoclonais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: MAbs Assunto da revista: ALERGIA E IMUNOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Suíça