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Systems analyses of the Fabry kidney transcriptome and its response to enzyme replacement therapy identified and cross-validated enzyme replacement therapy-resistant targets amenable to drug repurposing.
Delaleu, Nicolas; Marti, Hans-Peter; Strauss, Philipp; Sekulic, Miroslav; Osman, Tarig; Tøndel, Camilla; Skrunes, Rannveig; Leh, Sabine; Svarstad, Einar; Nowak, Albina; Gaspert, Ariana; Rusu, Elena; Kwee, Ivo; Rinaldi, Andrea; Flatberg, Arnar; Eikrem, Oystein.
Afiliação
  • Delaleu N; 2cSysBioMed, Contra, Switzerland; Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Marti HP; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.
  • Strauss P; Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Sekulic M; Department of Pathology and Cell Biology, Columbia University, New York, New York, USA.
  • Osman T; Department of Clinical Medicine, University of Bergen, Bergen, Norway.
  • Tøndel C; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
  • Skrunes R; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.
  • Leh S; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Pathology, Haukeland University Hospital, Bergen, Norway.
  • Svarstad E; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway.
  • Nowak A; Department of Endocrinology and Clinical Nutrition, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
  • Gaspert A; Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.
  • Rusu E; Department of Nephrology, Fundeni Clinical Institute, Bucharest, Romania; Department of Nephrology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
  • Kwee I; BigOmics Analytics, Lugano, Switzerland.
  • Rinaldi A; Institute of Oncology Research, Oncology Institute of Southern Switzerland, Università della Svizzera Italiana, Bellinzona, Switzerland.
  • Flatberg A; Central Administration, St. Olav's Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
  • Eikrem O; Department of Clinical Medicine, University of Bergen, Bergen, Norway; Department of Medicine, Haukeland University Hospital, Bergen, Norway. Electronic address: oystein.eikrem@uib.no.
Kidney Int ; 104(4): 803-819, 2023 10.
Article em En | MEDLINE | ID: mdl-37419447
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Fabry / Nefropatias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Kidney Int Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Noruega
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Fabry / Nefropatias Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Kidney Int Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Noruega