Pentoxifylline Inhibits TNF-&#945;/TGF-ß1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-&#954;B Pathway and <i>SERPINE1</i> Expression in CaSki Cells.

Palafox-Mariscal, Luis Arturo; Ortiz-Lazareno, Pablo Cesar; Jave-Suárez, Luis Felipe; Aguilar-Lemarroy, Adriana; Villaseñor-García, María Martha; Cruz-Lozano, José Roberto; González-Martínez, Karen Lilith; Méndez-Clemente, Aníbal Samael; Bravo-Cuellar, Alejandro; Hernández-Flores, Georgina

Pentoxifylline Inhibits TNF-α/TGF-ß1-Induced Epithelial-Mesenchymal Transition via Suppressing the NF-κB Pathway and SERPINE1 Expression in CaSki Cells.

Palafox-Mariscal, Luis Arturo; Ortiz-Lazareno, Pablo Cesar; Jave-Suárez, Luis Felipe; Aguilar-Lemarroy, Adriana; Villaseñor-García, María Martha; Cruz-Lozano, José Roberto; González-Martínez, Karen Lilith; Méndez-Clemente, Aníbal Samael; Bravo-Cuellar, Alejandro; Hernández-Flores, Georgina.

Afiliação

Palafox-Mariscal LA; Doctoral Program in Biomedical Sciences Orientation Immunology, University Center for Health Science (CUCS), University of Guadalajara (UdeG), 44340 Guadalajara, Jalisco, Mexico.
Ortiz-Lazareno PC; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
Jave-Suárez LF; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
Aguilar-Lemarroy A; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
Villaseñor-García MM; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
Cruz-Lozano JR; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
González-Martínez KL; Department of Pharmacobiology, University Center for Exact Sciences and Engineering (CUCEI), University of Guadalajara (UdeG), 44340 Guadalajara, Jalisco, Mexico.
Méndez-Clemente AS; Doctoral Program in Biomedical Sciences Orientation Immunology, University Center for Health Science (CUCS), University of Guadalajara (UdeG), 44340 Guadalajara, Jalisco, Mexico.
Bravo-Cuellar A; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.
Hernández-Flores G; Immunology Division, Biomedical Research Center West (CIBO), Mexican Social Security Institute, 44340 Guadalajara, Jalisco, Mexico.

Int J Mol Sci ; 24(13)2023 Jun 24.

Article em En | MEDLINE | ID: mdl-37445768

Assuntos

Pentoxifilina; Neoplasias do Colo do Útero; Feminino; Humanos; NF-kappa B/metabolismo; Fator de Necrose Tumoral alfa/farmacologia; Fator de Crescimento Transformador beta1/metabolismo; Transição Epitelial-Mesenquimal; Vimentina/metabolismo; Pentoxifilina/farmacologia; Neoplasias do Colo do Útero/tratamento farmacológico; Caderinas/metabolismo; Linhagem Celular Tumoral; Microambiente Tumoral; Inibidor 1 de Ativador de Plasminogênio/genética

Palavras-chave

CaSki cells; NF-κB; SERPINE1; epithelial-mesenchymal transition; pentoxifylline

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pentoxifilina / Neoplasias do Colo do Útero Limite: Female / Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2023 Tipo de documento: Article País de afiliação: México

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