Flubendazole inhibits PD-1 and suppresses melanoma growth in immunocompetent mice.

Li, Yue; Wu, Ben; Hossain, Md Jakir; Quagliata, Lily; O'Meara, Connor; Wilkins, Marc R; Corley, Susan; Khachigian, Levon M

Li, Yue; Wu, Ben; Hossain, Md Jakir; Quagliata, Lily; O'Meara, Connor; Wilkins, Marc R; Corley, Susan; Khachigian, Levon M.

Afiliação

Li Y; Vascular Biology and Translational Research, Department of Pathology, School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Wu B; Vascular Biology and Translational Research, Department of Pathology, School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Hossain MJ; Vascular Biology and Translational Research, Department of Pathology, School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Quagliata L; Vascular Biology and Translational Research, Department of Pathology, School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, 2052, Australia.
O'Meara C; Vascular Biology and Translational Research, Department of Pathology, School of Biomedical Sciences, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, 2052, Australia.
Wilkins MR; Department of Otorhinolaryngology, Head & Neck Surgery, Prince of Wales Hospital, Randwick, NSW, 2031, Australia.
Corley S; Systems Biology Initiative, Ramaciotti Centre for Genomics, University of New South Wales, Sydney, NSW, 2052, Australia.
Khachigian LM; Systems Biology Initiative, Ramaciotti Centre for Genomics, University of New South Wales, Sydney, NSW, 2052, Australia.

J Transl Med ; 21(1): 467, 2023 07 14.

Article em En | MEDLINE | ID: mdl-37452307

Assuntos

Melanoma; Neoplasias Cutâneas; Humanos; Animais; Camundongos; Melanoma/patologia; Antígeno B7-H1; Receptor de Morte Celular Programada 1/metabolismo; Fator de Transcrição AP-1; Camundongos Endogâmicos C57BL; Linhagem Celular Tumoral

Palavras-chave

Benzimidazole; Flubendazole; Melanoma; Programmed cell death protein-1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Melanoma Limite: Animals / Humans Idioma: En Revista: J Transl Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Austrália

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