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SF3B1 mutation and ATM deletion codrive leukemogenesis via centromeric R-loop dysregulation.
Cusan, Martina; Shen, Haifeng; Zhang, Bo; Liao, Aijun; Yang, Lu; Jin, Meiling; Fernandez, Mike; Iyer, Prajish; Wu, Yiming; Hart, Kevyn; Gutierrez, Catherine; Nik, Sara; Pruett-Miller, Shondra M; Stark, Jeremy; Obeng, Esther A; Bowman, Teresa V; Wu, Catherine J; Lin, Ren-Jang; Wang, Lili.
Afiliação
  • Cusan M; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Shen H; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Zhang B; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Liao A; Department of Hematology, Union Hospital Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
  • Yang L; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Jin M; Department of Hematology, Affiliated Shengjing Hospital of China Medical University, Shenyang, China.
  • Fernandez M; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Iyer P; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Wu Y; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Hart K; Irell and Manella Graduate School of Biological Sciences, Beckman Research Institute of the City of Hope, Duarte, California, USA.
  • Gutierrez C; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Nik S; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Pruett-Miller SM; Department of Systems Biology, Beckman Research Institute of the City of Hope, Monrovia, California, USA.
  • Stark J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
  • Obeng EA; Gottesman Institute for Stem Cell Biology and Regenerative Medicine and.
  • Bowman TV; Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, New York, USA.
  • Wu CJ; Department of Cell and Molecular Biology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
  • Lin RJ; Department of Cancer Genetics and Epigenetics, Beckman Research Institute of the City of Hope, Duarte, California, USA.
  • Wang L; Department of Oncology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
J Clin Invest ; 133(17)2023 09 01.
Article em En | MEDLINE | ID: mdl-37463047
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: J Clin Invest Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Estados Unidos