Complexation of Fluorofenidone by Cucurbit[7]uril and ß-Cyclodextrin: Keto-Enol Tautomerization to Enhance the Solubility.

Ma, Wen-Juan; Chen, Hua-Yu; Huang, Yong-Liang; Chen, Jia-Mei; Lu, Tong-Bu

Ma, Wen-Juan; Chen, Hua-Yu; Huang, Yong-Liang; Chen, Jia-Mei; Lu, Tong-Bu.

Afiliação

Ma WJ; Department of Pharmacy, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.
Chen HY; Department of Pharmacy, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou 350212, China.
Huang YL; Department of Dermatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.
Chen JM; Department of Medicinal Chemistry, Shantou University Medical College, Shantou, Guangdong 515041, P. R. China.
Lu TB; Department of Pharmacy, the First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China.

Mol Pharm ; 20(9): 4517-4527, 2023 09 04.

Article em En | MEDLINE | ID: mdl-37526016

Assuntos

Compostos Macrocíclicos; beta-Ciclodextrinas; Ratos; Animais; Solubilidade; beta-Ciclodextrinas/química; Compostos Macrocíclicos/química; Hidrocarbonetos Aromáticos com Pontes/química

Palavras-chave

crystal structure; cucurbit[7]uril; fluorofenidone; keto−enol tautomerization; ß-cyclodextrin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Macrocíclicos / Beta-Ciclodextrinas Limite: Animals Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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