Inhibitors of the Mechanistic Target of Rapamycin Can Ameliorate Bortezomib-Induced Peripheral Neuropathy.

Suzuki, Mari; Zhou, Zijian; Nagayasu, Kazuki; Shirakawa, Hisashi; Nakagawa, Takayuki; Kaneko, Shuji

Suzuki, Mari; Zhou, Zijian; Nagayasu, Kazuki; Shirakawa, Hisashi; Nakagawa, Takayuki; Kaneko, Shuji.

Afiliação

Suzuki M; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.
Zhou Z; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.
Nagayasu K; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.
Shirakawa H; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.
Nakagawa T; Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital.
Kaneko S; Department of Molecular Pharmacology, Graduate School of Pharmaceutical Sciences, Kyoto University.

Biol Pharm Bull ; 46(8): 1049-1056, 2023.

Article em En | MEDLINE | ID: mdl-37532556

Assuntos

Antineoplásicos; Bortezomib; Doenças do Sistema Nervoso Periférico; Animais; Camundongos; Antineoplásicos/efeitos adversos; Bortezomib/efeitos adversos; Inibidores de MTOR; Doenças do Sistema Nervoso Periférico/induzido quimicamente; Doenças do Sistema Nervoso Periférico/tratamento farmacológico; Doenças do Sistema Nervoso Periférico/metabolismo; Sirolimo/farmacologia; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

bortezomib; chemotherapy-induced peripheral neuropathy; drug repurposing; rapamycin; real-world data

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças do Sistema Nervoso Periférico / Bortezomib / Antineoplásicos Limite: Animals Idioma: En Revista: Biol Pharm Bull Assunto da revista: BIOQUIMICA / FARMACOLOGIA Ano de publicação: 2023 Tipo de documento: Article

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