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Design, synthesis, and biological evaluation of a series of benzofuran[3,2-d]pyrimidine-4(3H)-one derivatives containing thiosemicarbazone analogs as novel PARP-1 inhibitors.
Wang, Yuanjiang; Li, Kun; Xu, Wenqing; Gou, Shaohua.
Afiliação
  • Wang Y; Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China; Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, PR China.
  • Li K; Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
  • Xu W; Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China.
  • Gou S; Pharmaceutical Research Center and School of Chemistry and Chemical Engineering, Southeast University, Nanjing 211189, PR China; Jiangsu Province Hi-Tech Key Laboratory for Biomedical Research, Southeast University, Nanjing 211189, PR China. Electronic address: sgou@seu.edu.cn.
Bioorg Chem ; 139: 106759, 2023 10.
Article em En | MEDLINE | ID: mdl-37544273
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiossemicarbazonas / Benzofuranos / Inibidores de Poli(ADP-Ribose) Polimerases Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tiossemicarbazonas / Benzofuranos / Inibidores de Poli(ADP-Ribose) Polimerases Idioma: En Revista: Bioorg Chem Ano de publicação: 2023 Tipo de documento: Article