Preconditioning of radiotherapy enhances efficacy of B7-H3-CAR-T in treating solid tumor models.

Wang, Tian; Zhang, Kailu; You, Fengtao; Ma, Renyuxue; Yang, Nan; Tian, Shuaiyu; An, Gangli; Yang, Lin

Wang, Tian; Zhang, Kailu; You, Fengtao; Ma, Renyuxue; Yang, Nan; Tian, Shuaiyu; An, Gangli; Yang, Lin.

Afiliação

Wang T; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China; PersonGen BioTherapeutics Co., Ltd., Suzhou, PR China.
Zhang K; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China.
You F; PersonGen BioTherapeutics Co., Ltd., Suzhou, PR China.
Ma R; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China.
Yang N; PersonGen BioTherapeutics Co., Ltd., Suzhou, PR China.
Tian S; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China.
An G; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China.
Yang L; Cyrus Tang Hematology Center, Collaborative Innovation Center of Hematology, State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, PR China; PersonGen BioTherapeutics Co., Ltd., Suzhou, PR China. Electronic address: yanglin@suda.edu.cn.

Life Sci ; 331: 122024, 2023 Oct 15.

Article em En | MEDLINE | ID: mdl-37574043

Assuntos

Neoplasias Pancreáticas; Receptores de Antígenos Quiméricos; Humanos; Camundongos; Animais; Receptores de Antígenos Quiméricos/metabolismo; Antígenos B7; Imunoterapia Adotiva/métodos; Neoplasias Pancreáticas/radioterapia; Linhagem Celular Tumoral; Histonas; Microambiente Tumoral

Palavras-chave

B7-H3; CAR-T; Immunotherapy; Radiotherapy

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Receptores de Antígenos Quiméricos Limite: Animals / Humans Idioma: En Revista: Life Sci Ano de publicação: 2023 Tipo de documento: Article

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