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The added value of text from Dutch general practitioner notes in predictive modeling.
Seinen, Tom M; Kors, Jan A; van Mulligen, Erik M; Fridgeirsson, Egill; Rijnbeek, Peter R.
Afiliação
  • Seinen TM; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Kors JA; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • van Mulligen EM; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Fridgeirsson E; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
  • Rijnbeek PR; Department of Medical Informatics, Erasmus University Medical Center, Rotterdam, The Netherlands.
J Am Med Inform Assoc ; 30(12): 1973-1984, 2023 11 17.
Article em En | MEDLINE | ID: mdl-37587084
ABSTRACT

OBJECTIVE:

This work aims to explore the value of Dutch unstructured data, in combination with structured data, for the development of prognostic prediction models in a general practitioner (GP) setting. MATERIALS AND

METHODS:

We trained and validated prediction models for 4 common clinical prediction problems using various sparse text representations, common prediction algorithms, and observational GP electronic health record (EHR) data. We trained and validated 84 models internally and externally on data from different EHR systems.

RESULTS:

On average, over all the different text representations and prediction algorithms, models only using text data performed better or similar to models using structured data alone in 2 prediction tasks. Additionally, in these 2 tasks, the combination of structured and text data outperformed models using structured or text data alone. No large performance differences were found between the different text representations and prediction algorithms.

DISCUSSION:

Our findings indicate that the use of unstructured data alone can result in well-performing prediction models for some clinical prediction problems. Furthermore, the performance improvement achieved by combining structured and text data highlights the added value. Additionally, we demonstrate the significance of clinical natural language processing research in languages other than English and the possibility of validating text-based prediction models across various EHR systems.

CONCLUSION:

Our study highlights the potential benefits of incorporating unstructured data in clinical prediction models in a GP setting. Although the added value of unstructured data may vary depending on the specific prediction task, our findings suggest that it has the potential to enhance patient care.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clínicos Gerais Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Clínicos Gerais Tipo de estudo: Prognostic_studies / Qualitative_research / Risk_factors_studies Limite: Humans Idioma: En Revista: J Am Med Inform Assoc Assunto da revista: INFORMATICA MEDICA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Holanda