BRAF V600E is associated with higher incidence of second cancers in adults with Langerhans cell histiocytosis.
Blood
; 142(18): 1570-1575, 2023 11 02.
Article
em En
| MEDLINE
| ID: mdl-37595284
ABSTRACT
In this retrospective study, BRAF mutation status did not correlate with disease extent or (event-free) survival in 156 adults with Langerhans cell histiocytosis. BRAFV600E was associated with an increased incidence of second malignancies, often comprising hematological cancers, which may be clonally related.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Histiocitose de Células de Langerhans
/
Segunda Neoplasia Primária
Tipo de estudo:
Incidence_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Blood
Ano de publicação:
2023
Tipo de documento:
Article
País de afiliação:
Mongólia