Efficacy of Ustekinumab Optimization by 2 Initial Intravenous Doses in Adult Patients With Severe Crohn's Disease.

Ren, Haixia; Kang, Jian; Wang, Jing; Su, Juan; Zou, Liping; Yin, Anning; Li, Jiao; Zhou, Qian; Wang, Wei; Tang, Zhishun; Zhang, Jing; Lu, Yueyue; Yang, Yuanping; Qiu, Chengen; Ding, Yijuan; Dong, Weiguo; An, Ping

Ren, Haixia; Kang, Jian; Wang, Jing; Su, Juan; Zou, Liping; Yin, Anning; Li, Jiao; Zhou, Qian; Wang, Wei; Tang, Zhishun; Zhang, Jing; Lu, Yueyue; Yang, Yuanping; Qiu, Chengen; Ding, Yijuan; Dong, Weiguo; An, Ping.

Afiliação

Ren H; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.
Kang J; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Wang J; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Su J; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.
Zou L; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Yin A; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Li J; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.
Zhou Q; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Wang W; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Tang Z; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.
Zhang J; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Lu Y; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Yang Y; Department of Pathology, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Qiu C; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.
Ding Y; Key Laboratory of Hubei Province for Digestive System Disease, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
Dong W; Hubei Provincial Clinical Research Center for Digestive Disease Minimally Invasive Incision, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei Province, China.
An P; Department of Gastroenterology, Renmin Hospital of Wuhan University, 99 Zhangzhidong Road, Wuhan 430060, Hubei Province, China.

Inflamm Bowel Dis ; 2023 Aug 24.

Article em En | MEDLINE | ID: mdl-37619248

This study used an optimization strategy in severe adult Crohn's disease with 2 initial intravenous doses of ustekinumab. This new strategy proved to be effective and safe.

Palavras-chave

effectiveness; optimization; safety; severe Crohn's disease; ustekinumab

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Observational_studies / Prognostic_studies Idioma: En Revista: Inflamm Bowel Dis Assunto da revista: GASTROENTEROLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: China

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